Autism and Mitochondrial Disease

Autor/in	Haas, Richard H.
Titel	Autism and Mitochondrial Disease
Quelle	In: Developmental Disabilities Research Reviews, 16 (2010) 2, S.144-153 (10 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1940-5510
DOI	10.1002/ddrr.112
Schlagwörter	Autism; Mental Disorders; Diseases; Patients; Genetics; Language Impairments; Pervasive Developmental Disorders; Genetic Disorders; Interpersonal Competence; Behavior Problems; Metabolism; Immunization Programs; Children + Suchen Sie Ihr Suchwort? Autismus; Mental illness; Geisteskrankheit; Disease; Krankheit; Patient; Humangenetik; Speech disorder; Speech disorders; Speech disabilities; Speech disability; Speech handicap; Speech handicaps; Speech impairment; Speech impairments; Language handicaps; Sprachbehinderung; Interpersonale Kompetenz; Stoffwechsel; Immunisierung; Child; Kind; Kinder
Abstract	Autism spectrum disorder (ASD) as defined by the revised Diagnostic and Statistical Manual of Mental Disorders: DSM IVTR criteria (American Psychiatric Association [2000] Washington, DC: American Psychiatric Publishing) as impairment before the age of 3 in language development and socialization with the development of repetitive behaviors, appears to be increased in incidence and prevalence. Similarly, mitochondrial disorders are increasingly recognized. Although overlap between these disorders is to be expected, accumulating clinical, genetic, and biochemical evidence suggests that mitochondrial dysfunction in ASD is more commonly seen than expected. Some patients with ASD phenotypes clearly have genetic-based primary mitochondrial disease. This review will examine the data linking autism and mitochondria. (Contains 2 tables and 2 figures.) (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10