Analyzing Population Genetics Using the Mitochondrial Control Region and Bioinformatics

Autor/inn/en	Sato, Takumi; Phillips, Bonnie; Latourelle, Sandra M.; Elwess, Nancy L.
Titel	Analyzing Population Genetics Using the Mitochondrial Control Region and Bioinformatics
Quelle	In: Bioscene: Journal of College Biology Teaching, 36 (2010) 1, S.26-33 (8 Seiten)Infoseite zur Zeitschrift PDF als Volltext kostenfreie Datei Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1539-2422
Schlagwörter	College Science; Genetics; Biology; Information Science; Asians; Foreign Students; Inquiry; Active Learning; Student Projects; Research Projects; Scientific Research; Undergraduate Students; New York + Suchen Sie Ihr Suchwort? Humangenetik; Biologie; Informationswissenschaft; Asian; Asiat; Asiatin; Asiaten; Asiate; Aktives Lernen; Schulprojekt; Forschungsvorhaben
Abstract	The 14-base pair hypervariable region in mitochondrial DNA (mtDNA) of Asian populations, specifically Japanese and Chinese students at Plattsburgh State University, was examined. Previous research on this 14-base pair region showed it to be susceptible to mutations and as a result indicated direct correlation with specific ethnic populations. Earlier studies provided the 14-base pair region sequence analysis for Asians in general. This inquiry-based project was generated in a junior/senior college general genetics course. The project produced sequences of the 14-base pair hypervariable region for Japanese and Chinese populations, specifically. The investigation examined 28 Japanese and 27 Chinese international students. A Control group, consisting of 20 random students was also sampled. The 14-base pair hypervariable region for each sample was analyzed through comparison using bioinformatics. Analyzing the samples showed that, overall, 46% of the Japanese samples, 59% of the Chinese samples, and 75% of the Control samples had the same 14-base pair sequence. In addition to this, it was observed that the Japanese, Chinese, and Control group all had their own specific mutations within the 14-base pair hypervariable region. (Contains 3 figures and 2 tables.) (As Provided).
Anmerkungen	Association of College and Biology Educators. Web site: http://acube.org
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10