Optimization of Blocked Designs in fMRI Studies

Autor/inn/en	Maus, Barbel; van Breukelen, Gerard J. P.; Goebel, Rainer; Berger, Martijn P. F.
Titel	Optimization of Blocked Designs in fMRI Studies
Quelle	In: Psychometrika, 75 (2010) 2, S.373-390 (18 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0033-3123
DOI	10.1007/s11336-010-9159-3
Schlagwörter	Structural Equation Models; Diagnostic Tests; Visual Aids; Brain; Stimuli; Mathematical Models + Suchen Sie Ihr Suchwort? Diagnostic test; Diagnostischer Test; Anschauungsmaterial; Gehirn; Anreizsystem; Mathematical model; Mathematisches Modell
Abstract	Blocked designs in functional magnetic resonance imaging (fMRI) are useful to localize functional brain areas. A blocked design consists of different blocks of trials of the same stimulus type and is characterized by three factors: the length of blocks, i.e., number of trials per blocks, the ordering of task and rest blocks, and the time between trials within one block. Optimal design theory was applied to find the optimal combination of these three design factors. Furthermore, different error structures were used within a general linear model for the analysis of fMRI data, and the maximin criterion was applied to find designs which are robust against misspecification of model parameters. (Contains 1 table and 4 figures.) (As Provided).
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Update	2017/4/10