Lesion Neuroanatomy of the Sustained Attention to Response Task

Autor/inn/en	Molenberghs, Pascal; Gillebert, Celine R.; Schoofs, Hanne; Dupont, Patrick; Peeters, Ronald; Vandenberghe, Rik
Titel	Lesion Neuroanatomy of the Sustained Attention to Response Task
Quelle	In: Neuropsychologia, 47 (2009) 13, S.2866-2875 (10 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0028-3932
DOI	10.1016/j.neuropsychologia.2009.06.012
Schlagwörter	Reaction Time; Patients; Cognitive Processes; Neurological Impairments; Task Analysis; Attention Control; Neuropsychology; Attention Deficit Disorders; Hyperactivity; Brain; Injuries; Autism; Symptoms (Individual Disorders); Brain Hemisphere Functions; Measures (Individuals) + Suchen Sie Ihr Suchwort? Reaktionsvermögen; Patient; Cognitive process; Kognitiver Prozess; Neurodegenerative Erkrankung; Aufgabenanalyse; Aufmerksamkeitstest; Neuropsychologie; Attention deficit hyperactivity disorder; ADHS; Aufmerksamkeits-Defizit-Hyperaktivitäts-Störung; Aufmerksamkeitsstörung; Hyperaktivität; Gehirn; Autismus; Psychiatrische Symptomatik; Messdaten
Abstract	The Sustained Attention to Response task is a classical neuropsychological test that has been used by many centres to characterize the attentional deficits in traumatic brain injury, ADHD, autism and other disorders. During the SART a random series of digits 1-9 is presented repeatedly and subjects have to respond to each digit (go trial) except the digit "3" (no-go trial). Using voxel-based lesion symptom mapping (VLSM) in a consecutive series of 44 ischemic unifocal non-lacunar hemispheric stroke patients we determined the neuroanatomy of 4 SART parameters: commission and omission error rate, reaction time variability and post-error slowing. Lesions of the right inferior frontal gyrus significantly increased commission error rate. Lesions of the middle third of the right inferior frontal sulcus (IFS) reduced post-error slowing, a measure of how well subjects can utilize errors to adjust cognitive resource allocation. Omissions and reaction time variability had less localising value in our sample. To conclude, commission errors and post-error slowing in the SART mainly probe right inferior frontal integrity. (Contains 6 figures and 1 table.) (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10