Clinical Assessment of Autism in High-Risk 18-Month-Olds

Autor/inn/en	Brian, J.; Bryson, S. E.; Garon, N.; Roberts, W.; Smith, I. M.; Szatmari, P.; Zwaigenbaum, L.
Titel	Clinical Assessment of Autism in High-Risk 18-Month-Olds
Quelle	In: Autism: The International Journal of Research and Practice, 12 (2008) 5, S.433-456 (24 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1362-3613
DOI	10.1177/1362361308094500
Schlagwörter	Siblings; Observation; Autism; Infants; Discriminant Analysis; Toddlers; Symptoms (Individual Disorders); Evaluation Methods; Pervasive Developmental Disorders; At Risk Persons; Social Behavior; Behavior Problems; Psychomotor Skills; Interpersonal Communication; Personality Traits + Suchen Sie Ihr Suchwort? Sibling; Geschwister; Beobachtung; Autismus; Infant; Toddler; Toddlers; Kleinkind; Diskriminanzanalyse; Infants; Psychiatrische Symptomatik; Risikogruppe; Social behaviour; Soziales Verhalten; Psychomotorische Aktivität; Interpersonale Kommunikation; Individual characteristics; Personality characteristic; Persönlichkeitsmerkmal
Abstract	Earlier intervention improves outcomes for children with autism spectrum disorders (ASDs), but existing identification tools are at the limits of standardization with 18-month-olds. We assessed potential behavioural markers of ASD at 18 months in a high-risk cohort of infant siblings of children with ASD. Prospective data were collected using the Autism Diagnostic Observation Schedule (ADOS) and Autism Observation Scale for Infants (AOSI) on 155 infant siblings and 73 low-risk controls at 18 months. Infants were classified into three groups (ASD sibs, non-ASD sibs, controls) based on blind best-estimate diagnosis at age 3. Fisher's exact tests, followed by discriminant function analyses, revealed that the majority of informative ADOS items came from the social and behavioural domains, and AOSI items measuring behavioural reactivity and motor control contributed additional information. Findings highlight the importance of considering not only social-communication deficits, but also basic dimensions of temperament including state regulation and motor control when assessing toddlers with suspected ASD. (Contains 2 figures and 7 tables.) (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10