Literaturnachweis - Detailanzeige
| Autor/inn/en | Briand, Lisa A.; Robinson, Terry E.; Maren, Stephen |
|---|---|
| Titel | Enhancement of Auditory Fear Conditioning after Housing in a Complex Environment Is Attenuated by Prior Treatment with Amphetamine |
| Quelle | In: Learning & Memory, 12 (2005) 6, S.553-556 (4 Seiten)
PDF als Volltext |
| Sprache | englisch |
| Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
| ISSN | 1072-0502 |
| DOI | 10.1101/lm.95905 |
| Schlagwörter | Stimuli; Housing; Difficulty Level; Conditioning; Fear; Cognitive Processes; Animals; Drug Use; Drug Abuse; Auditory Stimuli |
| Abstract | Prior exposure to drugs of abuse has been shown to occlude the structural plasticity associated with living in a complex environment. Amphetamine treatment may also occlude some cognitive advantages normally associated with living in a complex environment. To test this hypothesis we examined the influence of prior exposure to amphetamine on fear conditioning in rats housed in either a standard or complex environment. Housing in a complex environment facilitated fear learning to an auditory conditioned stimulus (CS), but not to the training context, relative to animals housed singly or in a social group. Prior treatment with amphetamine eliminated this effect. These results indicate that living in a complex environment facilitates conditional freezing to an auditory CS, and that this effect is abolished by pretreatment with amphetamine. (Contains 4 figures.) (Author). |
| Anmerkungen | Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://www.learnmem.org/ |
| Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
| Update | 2017/4/10 |
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