Contributions of Striatal Subregions to Place and Response Learning

Autor/inn/en	Yin, Henry H.; Knowlton, Barbara J.
Titel	Contributions of Striatal Subregions to Place and Response Learning
Quelle	In: Learning & Memory, 11 (2004) 4, S.459-463 (5 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
Schlagwörter	Nonverbal Learning; Behavioral Science Research; Neurological Impairments; Spatial Ability; Tests; Brain; Cognitive Processes; Surgery; Animals; Memory + Suchen Sie Ihr Suchwort? Neurodegenerative Erkrankung; Räumliches Vorstellungsvermögen; Examination; Prüfung; Examen; Gehirn; Cognitive process; Kognitiver Prozess; Chirurgie; Animal; Tier; Tiere; Gedächtnis
Abstract	The involvement of different subregions of the striatum in place and response learning was examined using a T-maze. Rats were given NMDA lesions of the dorsolateral striatum (DLS), anterior dorsomedial striatum (ADMS), posterior dorsomedial striatum (PDMS), or sham surgery. They were then trained to retrieve food from the west arm of the maze, starting from the south arm, by turning left at the choice point. After 7 d of training, with four trials a day, a probe test was given in which the starting arm is inserted as the north arm, at the opposite side of the maze. A left turn would indicate a "response" strategy; a right turn, a "place" strategy. The rats were then trained for 7 more days, followed by a second probe test. Unlike rats in the other groups, most of the rats in the PDMS group turned left, using the response strategy on both probe tests. These results suggest that the PDMS plays a role in spatially guided behavior. (Contains 3 figures.) (Author).
Anmerkungen	Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://www.learnmem.org/
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10