Risperidone and Adaptive Behavior in Children with Autism

Autor/inn/en	Williams, Susan K.; Scahill, Lawrence; Vitiello, Benedetto; Aman, Michael G.; Arnold, L. Eugene; McDougle, Christopher J.; McCracken, James T.; Tierney, Elaine; Ritz, Louise; Posey, David J.; Swiezy, Naomi B.; Hollway, Jill; Cronin, Pegeen; Ghuman, Jaswinder; Wheeler, Courtney; Cicchetti, Domenic; Sparrow, Sara
Titel	Risperidone and Adaptive Behavior in Children with Autism
Quelle	In: Journal of the American Academy of Child and Adolescent Psychiatry, 45 (2006) 4, S.431-439 (9 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0890-8567
Schlagwörter	Daily Living Skills; Behavior Problems; Socialization; Autism; Drug Therapy; Pervasive Developmental Disorders; Children; Behavior Disorders; Behavior Modification; Outcomes of Treatment; Interpersonal Competence; Self Destructive Behavior; Antisocial Behavior; Communication Skills; Adjustment (to Environment); Vineland Adaptive Behavior Scales + Suchen Sie Ihr Suchwort? Alltagsfertigkeit; Socialisation; Sozialisation; Autismus; Child; Kind; Kinder; Behaviour modification; Verhaltensänderung; Interpersonale Kompetenz; Self destrucive behaviour; Selbstzerstörung; Kommunikationsstil
Abstract	Objective: To evaluate the impact of risperidone on adaptive behavior in children with autistic disorder who have serious behavior problems and to examine different methods of scoring the Vineland Adaptive Behavior Scales to measure change. Method: Forty-eight children (5 years to 16 years, 5 months) who showed behavioral improvement during acute treatment with risperidone were followed for 6 months and assessed with the Vineland Scales. Results: Raw scores, age-equivalents, and special norm percentile scores all showed significant increases in adaptive behavior in the areas of communication, daily living skills, and socialization (p less than 0.01). During a period of 6 to 8 months, children gained an average of 7.8 age-equivalent months in the area of socialization, a greater than 6% improvement beyond what would be expected based on baseline growth rates. Conclusions: Although limited by the absence of a control group, these results suggest that risperidone may improve adaptive skills in children with autistic disorder accompanied by serious behavioral problems. Vineland age-equivalent scores appear to be most useful in assessing change with treatment over time. (Contains 2 tables.) (Author).
Anmerkungen	Lippincott Williams & Wilkins. P.O. Box 1600, Hagerstown, MD 21741. Tel: 800-638-3030; Tel: 301-223-2300; Fax: 301-223-2400; Web site: http://www.lww.com/product/?0890-8567
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10