Synthesis, Antimicrobial Properties, and Biomedical Applicability of Ag(I) Cyanoximate Complexes

Autor/inn/en	Young, Karin J.; Habgood, Laurel G.; Stensaas, Kristina L.; Villanueva, Omar; Weigand, Willis
Titel	Synthesis, Antimicrobial Properties, and Biomedical Applicability of Ag(I) Cyanoximate Complexes
Quelle	In: Journal of Chemical Education, 98 (2021) 9, S.2997-3003 (7 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Young, Karin J.) ORCID (Villanueva, Omar)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0021-9584
DOI	10.1021/acs.jchemed.1c00186
Schlagwörter	Chemistry; Biomedicine; Laboratory Experiments; Biochemistry; Science Instruction; Teaching Methods; Comparative Analysis; Guidelines; Heat; Water; Cost Effectiveness; Tests + Suchen Sie Ihr Suchwort? Chemie; Biomedizin; Laboratory work; Laborarbeit; Biochemie; Teaching of science; Science education; Natural sciences Lessons; Naturwissenschaftlicher Unterricht; Teaching method; Lehrmethode; Unterrichtsmethode; Richtlinien; Hitze; Wasser; Kosten-Nutzen-Analyse; Kosten-Nutzen-Denken; Examination; Prüfung; Examen
Abstract	In this laboratory experiment, students evaluated three silver(I) complexes as potential additives for dental adhesives based on bacterial growth inhibition, heat stability, water insolubility, and cost-effectiveness. Each student prepared and analyzed a cyanoxime ligand and its corresponding silver(I) complex. Students characterized the antibacterial activity of the silver complexes against "E." coli using a Kirby-Bauer disk-diffusion test. Laboratory data were shared among students to compare observed properties to determine which derivative is the most suitable. This multiweek experiment was used in inorganic chemistry laboratory courses to demonstrate the application of inorganic chemistry to biomedicine. The framework of the experiment was developed by a multi-institutional collaboration, and we highlight how the general procedures of the experiment were adapted to meet the needs of varying courses and contexts. (As Provided).
Anmerkungen	Division of Chemical Education, Inc. and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01