Literaturnachweis - Detailanzeige
Autor/inn/en | Aran, Adi; Cassuto, Hanoch; Lubotzky, Asael; Wattad, Nadia; Hazan, Esther |
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Titel | Brief Report: Cannabidiol-Rich Cannabis in Children with Autism Spectrum Disorder and Severe Behavioral Problems--A Retrospective Feasibility Study |
Quelle | In: Journal of Autism and Developmental Disorders, 49 (2019) 3, S.1284-1288 (5 Seiten)
PDF als Volltext |
Zusatzinformation | ORCID (Aran, Adi) |
Sprache | englisch |
Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
ISSN | 0162-3257 |
DOI | 10.1007/s10803-018-3808-2 |
Schlagwörter | Behavior Problems; Autism; Pervasive Developmental Disorders; Sleep; Psychosis; Drug Therapy; Marijuana; Outcomes of Treatment; Parent Attitudes; Eating Habits; Patients |
Abstract | Anecdotal evidence of successful cannabis treatment in autism spectrum disorder (ASD) are accumulating but clinical studies are lacking. This retrospective study assessed tolerability and efficacy of cannabidiol-rich cannabis, in 60 children with ASD and severe behavioral problems (age = 11.8 ± 3.5, range 5.0-17.5; 77% low functioning; 83% boys). Efficacy was assessed using the Caregiver Global Impression of Change scale. Adverse events included sleep disturbances (14%) irritability (9%) and loss of appetite (9%). One girl who used higher tetrahydrocannabinol had a transient serious psychotic event which required treatment with an antipsychotic. Following the cannabis treatment, behavioral outbreaks were much improved or very much improved in 61% of patients. This preliminary study supports feasibility of CBD-based cannabis trials in children with ASD. (As Provided). |
Anmerkungen | Springer. Available from: Springer Nature. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/ |
Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
Update | 2020/1/01 |