Development of a Patient-Centered Conceptual Model of the Impact of Living with Autism Spectrum Disorder

Autor/inn/en	McDougall, Fiona; Willgoss, Thomas; Hwang, Steve; Bolognani, Federico; Murtagh, Lorraine; Anagnostou, Evdokia; Rofail, Diana
Titel	Development of a Patient-Centered Conceptual Model of the Impact of Living with Autism Spectrum Disorder
Quelle	In: Autism: The International Journal of Research and Practice, 22 (2018) 8, S.953-969 (17 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1362-3613
DOI	10.1177/1362361317718987
Schlagwörter	Autism; Pervasive Developmental Disorders; Patients; Adolescents; Adults; Children; Parents; Symptoms (Individual Disorders); Communication Problems; Interpersonal Competence; Behavior Problems; Emotional Response; Cognitive Ability; Physical Disabilities; Daily Living Skills; Social Life; Interpersonal Relationship + Suchen Sie Ihr Suchwort? Autismus; Patient; Adolescent; Adolescence; Adoleszenz; Jugend; Jugendalter; Jugendlicher; Child; Kind; Kinder; Eltern; Psychiatrische Symptomatik; Kommunikationsbarriere; Interpersonale Kompetenz; Emotionales Verhalten; Denkfähigkeit; Physical handicap; Körperbehinderung; Alltagsfertigkeit; Soziales Leben; Interpersonal relation; Interpersonal relations; Interpersonelle Beziehung; Zwischenmenschliche Beziehung
Abstract	The aim of this study was to generate a patient-centered conceptual model of the impact of living with autism spectrum disorder, which can be used to support the selection of outcome measures for clinical trials. Following an initial literature review to identify preliminary concepts and inform an interview guide, in-depth face-to-face interviews were conducted with adolescents and adults with autism spectrum disorder (IQ ? 70) (n = 10), as well as parents of children, adolescents, and adults with autism spectrum disorder (IQ ? 70) (n = 26). Data were analyzed using established qualitative research methods. The resultant conceptual model contains three interrelated domains reflecting core symptoms of autism spectrum disorder (communication deficits, socialization deficits, and restrictive, repetitive patterns of behavior), three domains reflecting associated symptoms of autism spectrum disorder (physical, cognitive, and emotional/behavioral), and three domains representing the impacts of living with autism spectrum disorder (impacts on activities of daily living, school/work, and social life). Interview respondents also cited social communication deficits as priority targets for new treatments. The conceptual model provides a patient-centered perspective of relevant concepts of autism spectrum disorder from the perspectives of people with autism spectrum disorder and their parents and offers a valuable tool for identifying valid patient-centered outcome measures for future clinical trials. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01