Association of Autism with Maternal Infections, Perinatal and Other Risk Factors: A Case-Control Study

Autor/inn/en	Guisso, Dikran Richard; Saadeh, Fadi S.; Saab, Dahlia; El Deek, Joud; Chamseddine, Sarah; El Hassan, Hadi Abou; Majari, Ghidaa; Boustany, Rose-Mary
Titel	Association of Autism with Maternal Infections, Perinatal and Other Risk Factors: A Case-Control Study
Quelle	In: Journal of Autism and Developmental Disorders, 48 (2018) 6, S.2010-2021 (12 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Boustany, Rose-Mary)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-017-3449-x
Schlagwörter	Autism; Case Studies; Screening Tests; Mental Disorders; Correlation; Risk; Mothers; Social Support Groups; Pregnancy; Prenatal Influences; Pervasive Developmental Disorders; Early Intervention; Clinics; Foreign Countries; Control Groups; Genetics; Diseases; Perinatal Influences; Statistical Analysis; Birth Order; Lebanon + Suchen Sie Ihr Suchwort? Autismus; Case study; Fallstudie; Case Study; Screening-Verfahren; Mental illness; Geisteskrankheit; Korrelation; Risiko; Mother; Mutter; Social support; Soziale Unterstützung; Schwangerschaft; Pränataler Einfluss; Ausland; Humangenetik; Disease; Krankheit; Perinatalperiode; Statistische Analyse; Geburtenfolge; Libanon
Abstract	This case-control study explores the association between pregnancy/birth complications and other factors with Autism Spectrum Disorder (ASD) in Lebanese subjects aged 2-18 years. Researchers interviewed 136 ASD cases from the American University of Beirut Medical Center Special Kids Clinic, and 178 controls selected by systematic digit dialing in the Greater-Beirut area. Male gender (Adjusted Odds Ratio [95% CI]: 3.9 [2.2-7.0]); postpartum feeding difficulties (2.5 [1.2-5.4]); maternal infections/complications during pregnancy (2.9 [1.5-5.5], 2.1 [1.1-3.9]); consanguinity (2.5 [1.0-6.0]); family history of psychiatric disorders (2.2 [1.1-4.4]) were risk factors for ASD. Being born first/second (0.52 [0.28-0.95]) and maternal psychological support during pregnancy (0.49 [0.27-0.89]) were negatively associated with ASD. Identifying ASD correlates is crucial for instigating timely screening and subsequent early intervention. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01