Association between Air Pollution Exposure, Cognitive and Adaptive Function, and ASD Severity among Children with Autism Spectrum Disorder

Autor/inn/en	Kerin, Tara; Volk, Heather; Li, Weiyan; Lurmann, Fred; Eckel, Sandrah; McConnell, Rob; Hertz-Picciotto, Irva
Titel	Association between Air Pollution Exposure, Cognitive and Adaptive Function, and ASD Severity among Children with Autism Spectrum Disorder
Quelle	In: Journal of Autism and Developmental Disorders, 48 (2018) 1, S.137-150 (14 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-017-3304-0
Schlagwörter	Prenatal Influences; Pollution; Autism; Pervasive Developmental Disorders; Severity (of Disability); Cognitive Ability; Adjustment (to Environment); Motor Development; Young Children; Behavior Rating Scales; Diagnostic Tests; Observation; Scores; Mullen Scales of Early Learning; Vineland Adaptive Behavior Scales; Autism Diagnostic Observation Schedule + Suchen Sie Ihr Suchwort? Pränataler Einfluss; Schadstoffbelastung; Autismus; Schweregrad; Denkfähigkeit; Motorische Entwicklung; Frühe Kindheit; Diagnostic test; Diagnostischer Test; Beobachtung
Abstract	Prenatal exposure to air pollution has been associated with autism spectrum disorder (ASD) risk but no study has examined associations with ASD severity or functioning. Cognitive ability, adaptive functioning, and ASD severity were assessed in 327 children with ASD from the Childhood Autism Risks from Genetics and the Environment study using the Mullen Scales of Early Learning (MSEL), the Vineland Adaptive Behavior Scales (VABS), and the Autism Diagnostic Observation Schedule calibrated severity score. Estimates of nitrogen dioxide (NO[subscript 2]), particulate matter (PM[subscript 2.5] and PM[subscript 10]), ozone, and near-roadway air pollution were assigned to each trimester of pregnancy and first year of life. Increasing prenatal and first year NO[subscript 2] exposures were associated with decreased MSEL and VABS scores. Increasing PM[subscript 10] exposure in the third trimester was paradoxically associated with improved performance on the VABS. ASD severity was not associated with air pollution exposure. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01