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Autor/inn/enWiggins, Lisa D.; Tian, Lin H.; Levy, Susan E.; Rice, Catherine; Lee, Li-Ching; Schieve, Laura; Pandey, Juhi; Daniels, Julie; Blaskey, Lisa; Hepburn, Susan; Landa, Rebecca; Edmondson-Pretzel, Rebecca; Thompson, William
TitelHomogeneous Subgroups of Young Children with Autism Improve Phenotypic Characterization in the Study to Explore Early Development
QuelleIn: Journal of Autism and Developmental Disorders, 47 (2017) 11, S.3634-3645 (12 Seiten)
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Spracheenglisch
Dokumenttypgedruckt; online; Zeitschriftenaufsatz
ISSN0162-3257
DOI10.1007/s10803-017-3280-4
SchlagwörterYoung Children; Autism; Pervasive Developmental Disorders; Homogeneous Grouping; Child Development; Diagnostic Tests; Disability Identification; Delayed Speech; Developmental Delays; Psychomotor Skills; Genetics; Early Childhood Education
AbstractThe objective of this study was to identify homogenous classes of young children with autism spectrum disorder (ASD) to improve phenotypic characterization. Children were enrolled in the Study to Explore Early Development between 2 and 5 years of age. 707 children were classified with ASD after a comprehensive evaluation with strict diagnostic algorithms. Four classes of children with ASD were identified from latent class analysis: "mild language delay with cognitive rigidity," "mild language and motor delay with dysregulation," "general developmental delay," and "significant developmental delay with repetitive motor behaviors." We conclude that a four-class phenotypic model of children with ASD best describes our data and improves phenotypic characterization of young children with ASD. Implications for screening, diagnosis, and research are discussed. (As Provided).
AnmerkungenSpringer. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail: service-ny@springer.com; Web site: http://www.springerlink.com
Erfasst vonERIC (Education Resources Information Center), Washington, DC
Update2020/1/01
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