Gray Matter Characteristics in Mid and Old Aged Adults with ASD

Autor/inn/en	Koolschijn, P. Cédric M. P.; Geurts, Hilde M.
Titel	Gray Matter Characteristics in Mid and Old Aged Adults with ASD
Quelle	In: Journal of Autism and Developmental Disorders, 46 (2016) 8, S.2666-2678 (13 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-016-2810-9
Schlagwörter	Adults; Older Adults; Pervasive Developmental Disorders; Case Studies; Brain; Statistical Analysis; Anatomy; Children; Adolescents; Comparative Analysis; Autism; Foreign Countries; Intelligence Tests; Diagnostic Tests; Observation; Correlation; Intelligence Quotient; Netherlands (Amsterdam); Autism Diagnostic Observation Schedule; Wechsler Adult Intelligence Scale + Suchen Sie Ihr Suchwort? Älterer Erwachsener; Case study; Fallstudie; Case Study; Gehirn; Statistische Analyse; Anatomie; Child; Kind; Kinder; Adolescent; Adolescence; Adoleszenz; Jugend; Jugendalter; Jugendlicher; Autismus; Ausland; Intelligence test; Intelligenztest; Diagnostic test; Diagnostischer Test; Beobachtung; Korrelation; Intelligenzquotient
Abstract	It is widely acknowledged that the brain anatomy of children and adolescents with autism spectrum disorder (ASD) shows a different developmental pattern then typical age-matched peers. There is however, a paucity of studies examining gray matter in mid and late adulthood in ASD. In this cross-sectional neuroimaging study, we, performed vertex-wise whole-brain and region-of-interest analyses of cortical volume, thickness, surface area, and gyrification index in 51 adults with and 49 without ASD, between 30 and 75 years. There was significant age-related volume loss and cortical thinning, but there were no group differences. The lack of significant anatomical differences between intellectual able individuals with and without ASD, suggests that ASD is not (strongly) related to gray matter morphology in mid and late adulthood. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01