The Association between Epilepsy and Autism Symptoms and Maladaptive Behaviors in Children with Autism Spectrum Disorder

Autor/inn/en	Viscidi, Emma W.; Johnson, Ashley L.; Spence, Sarah J.; Buka, Stephen L.; Morrow, Eric M.; Triche, Elizabeth W.
Titel	The Association between Epilepsy and Autism Symptoms and Maladaptive Behaviors in Children with Autism Spectrum Disorder
Quelle	In: Autism: The International Journal of Research and Practice, 18 (2014) 8, S.996-1006 (11 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1362-3613
DOI	10.1177/1362361313508027
Schlagwörter	Symptoms (Individual Disorders); Autism; Pervasive Developmental Disorders; Epilepsy; Correlation; Children; Comorbidity; Behavior Problems; Intelligence Quotient; Hyperactivity; Comparative Analysis; Mental Retardation; Severity (of Disability); Asperger Syndrome; Clinics; At Risk Persons; Aberrant Behavior Checklist; Mullen Scales of Early Learning; Autism Diagnostic Observation Schedule; Wechsler Intelligence Scale for Children + Suchen Sie Ihr Suchwort? Psychiatrische Symptomatik; Autismus; Epilepsie; Korrelation; Child; Kind; Kinder; Intelligenzquotient; Hyperaktivität; Geistige Behinderung; Schweregrad; Asperger-Syndrom; Risikogruppe
Abstract	Epilepsy is common in children with autism spectrum disorder (ASD) but little is known about how seizures impact the autism phenotype. The association between epilepsy and autism symptoms and associated maladaptive behaviors was examined in 2,645 children with ASD, of whom 139 had epilepsy, from the Simons Simplex Collection. Children with ASD and epilepsy had significantly more autism symptoms and maladaptive behaviors than children without epilepsy. However, after adjusting for IQ, only hyperactivity symptoms remained significantly increased (13% higher) in the epilepsy group. Among children with ASD without co-occurring intellectual disability, children with epilepsy had significantly more irritability (20% higher) and hyperactivity (24% higher) symptoms. This is the largest study to date comparing the autism phenotype in children with ASD with and without epilepsy. Children with ASD and epilepsy showed greater impairment than children without epilepsy, which was mostly explained by the lower IQ of the epilepsy group. These findings have important clinical implications for patients with ASD. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10