Pattern Recognition Receptors in Innate Immunity, Host Defense, and Immunopathology

Autor/inn/en	Suresh, Rahul; Mosser, David M.
Titel	Pattern Recognition Receptors in Innate Immunity, Host Defense, and Immunopathology
Quelle	In: Advances in Physiology Education, 37 (2013) 4, S.284-291 (8 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1043-4046
DOI	10.1152/advan.00058.2013
Schlagwörter	Pathology; Immunization Programs; Pattern Recognition; Prevention; Disease Control; Role; Physiology; Genetics; Science Instruction; Molecular Structure; Cytology + Suchen Sie Ihr Suchwort? Pathologie; Immunisierung; Mustererkennung; Prävention; Vorbeugung; Rollen; Physiologie; Humangenetik; Teaching of science; Science education; Natural sciences Lessons; Naturwissenschaftlicher Unterricht; Zytologie
Abstract	Infection by pathogenic microbes initiates a set of complex interactions between the pathogen and the host mediated by pattern recognition receptors. Innate immune responses play direct roles in host defense during the early stages of infection, and they also exert a profound influence on the generation of the adaptive immune responses that ensue. An improved understanding of the pattern recognition receptors that mediate innate responses and their downstream effects after receptor ligation has the potential to lead to new ways to improve vaccines and prevent autoimmunity. This review focuses on the control of innate immune activation and the role that innate immune receptors play in helping to maintain tissue homeostasis. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10