A Pilot Randomized Controlled Trial of Omega-3 Fatty Acids for Autism Spectrum Disorder

Autor/inn/en	Bent, Stephen; Bertoglio, Kiah; Ashwood, Paul; Bostrom, Alan; Hendren, Robert L.
Titel	A Pilot Randomized Controlled Trial of Omega-3 Fatty Acids for Autism Spectrum Disorder
Quelle	In: Journal of Autism and Developmental Disorders, 41 (2011) 5, S.545-554 (10 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-010-1078-8
Schlagwörter	Autism; Hyperactivity; Food; Pervasive Developmental Disorders; Children; Comparative Analysis; Correlation; Outcomes of Treatment; Aberrant Behavior Checklist + Suchen Sie Ihr Suchwort? Autismus; Hyperaktivität; Lebensmittel; Child; Kind; Kinder; Korrelation
Abstract	We conducted a pilot randomized controlled trial to determine the feasibility and initial safety and efficacy of omega-3 fatty acids (1.3 g/day) for the treatment of hyperactivity in 27 children ages 3-8 with autism spectrum disorder (ASD). After 12 weeks, hyperactivity, as measured by the Aberrant Behavior Checklist, improved 2.7 (plus or minus 4.8) points in the omega-3 group compared to 0.3 (plus or minus 7.2) points in the placebo group (p = 0.40; effect size = 0.38). Correlations were found between decreases in five fatty acid levels and decreases in hyperactivity, and the treatment was well tolerated. Although this pilot study did not find a statistically significant benefit from omega-3 fatty acids, the small sample size does not rule out small to moderate beneficial effects. (Contains 4 tables and 1 figure.) (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10