Emotional Arousal Impairs Association Memory: Roles of Prefrontal Cortex Regions

Autor/inn/en	Fujiwara, Esther; Madan, Christopher R.; Caplan, Jeremy B.; Sommer, Tobias
Titel	Emotional Arousal Impairs Association Memory: Roles of Prefrontal Cortex Regions
Quelle	In: Learning & Memory, 28 (2021) 3, S.76-81 (6 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Fujiwara, Esther) ORCID (Madan, Christopher R.) ORCID (Caplan, Jeremy B.) ORCID (Sommer, Tobias)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
Schlagwörter	Emotional Response; Arousal Patterns; Neurological Impairments; Paired Associate Learning; Memory; Brain Hemisphere Functions; Conflict Resolution + Suchen Sie Ihr Suchwort? Emotionales Verhalten; Neurodegenerative Erkrankung; Gedächtnis; Conflict solving; Konfliktlösung; Konfliktregelung
Abstract	The brain processes underlying impairing effects of emotional arousal on associative memory were previously attributed to two dissociable routes using high-resolution fMRI of the MTL (Madan et al. 2017). Extrahippocampal MTL regions supporting associative encoding of neutral pairs suggested unitization; conversely, associative encoding of negative pairs involved compensatory hippocampal activity. Here, whole-brain fMRI revealed prefrontal contributions: dmPFC was more involved in hippocampal-dependent negative pair learning and vmPFC in extrahippocampal neutral pair learning. Successful encoding of emotional memory associations may require emotion regulation/conflict resolution (dmPFC), while neutral memory associations may be accomplished by anchoring new information to prior knowledge (vmPFC). (As Provided).
Anmerkungen	Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://learnmem.cshlp.org
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01