Gastrointestinal Dysfunctions as a Risk Factor for Sleep Disorders in Children with Idiopathic Autism Spectrum Disorder: A Retrospective Cohort Study

Autor/inn/en	McCue, Lena M.; Flick, Louise H.; Twyman, Kimberly A.; Xian, Hong
Titel	Gastrointestinal Dysfunctions as a Risk Factor for Sleep Disorders in Children with Idiopathic Autism Spectrum Disorder: A Retrospective Cohort Study
Quelle	In: Autism: The International Journal of Research and Practice, 21 (2017) 8, S.1010-1020 (11 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1362-3613
DOI	10.1177/1362361316667061
Schlagwörter	Risk; Sleep; Autism; Pervasive Developmental Disorders; Symptoms (Individual Disorders); Medical Evaluation; Diseases; Quality of Life; Incidence; Severity (of Disability); Age Differences; Gender Differences; Comparative Analysis; Identification; Behavior Problems; Children; Adolescents; Young Children; Toddlers; Statistical Analysis + Suchen Sie Ihr Suchwort? Risiko; Schlaf; Autismus; Psychiatrische Symptomatik; Disease; Krankheit; Lebensqualität; Vorkommen; Schweregrad; Age; Difference; Age difference; Altersunterschied; Geschlechterkonflikt; Identifikation; Identifizierung; Child; Kind; Kinder; Adolescent; Adolescence; Adoleszenz; Jugend; Jugendalter; Jugendlicher; Frühe Kindheit; Infant; Infants; Toddler; Kleinkind; Statistische Analyse
Abstract	Sleep disorders often co-occur with autism spectrum disorder. They further exacerbate autism spectrum disorder symptoms and interfere with children's and parental quality of life. This study examines whether gastrointestinal dysfunctions increase the odds of having sleep disorders in 610 children with idiopathic autism spectrum disorder, aged 2-18 years, from the Autism Genetic Resource Exchange research program. The adjusted odds ratio for sleep disorder among those with gastrointestinal dysfunctions compared to those without was 1.74 (95% confidence interval: 1.22-2.48). In addition, the odds of having multiple sleep disorder symptoms among children with gastrointestinal dysfunctions, adjusted for age, gender, behavioral problems, bed wetting, current and past supplements, and current and past medications for autism spectrum disorder symptoms were 1.75 (95% confidence interval: 1.10-2.79) compared to children without gastrointestinal dysfunctions. Early detection and treatment of gastrointestinal dysfunctions in autism spectrum disorder may be means to reduce prevalence and severity of sleep problems and improve quality of life and developmental outcomes in this population. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01