Literaturnachweis - Detailanzeige
Autor/inn/en | Reichelt, Amy C.; Morris, Margaret J.; Westbrook, Reginald Frederick |
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Titel | Daily Access to Sucrose Impairs Aspects of Spatial Memory Tasks Reliant on Pattern Separation and Neural Proliferation in Rats |
Quelle | In: Learning & Memory, 23 (2016) 7, S.386-390 (5 Seiten)
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Sprache | englisch |
Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
ISSN | 1072-0502 |
DOI | 10.1101/lm.042416.116 |
Schlagwörter | Animals; Spatial Ability; Control Groups; Memory; Dietetics; Visual Discrimination; Biochemistry; Brain Hemisphere Functions; Interference (Learning); Task Analysis; Novelty (Stimulus Dimension) |
Abstract | High sugar diets reduce hippocampal neurogenesis, which is required for minimizing interference between memories, a process that involves "pattern separation." We provided rats with 2 h daily access to a sucrose solution for 28 d and assessed their performance on a spatial memory task. Sucrose consuming rats discriminated between objects in novel and familiar locations when there was a large spatial separation between the objects, but not when the separation was smaller. Neuroproliferation markers in the dentate gyrus of the sucrose-consuming rats were reduced relative to controls. Thus, sucrose consumption impaired aspects of spatial memory and reduced hippocampal neuroproliferation. (As Provided). |
Anmerkungen | Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://learnmem.cshlp.org |
Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
Update | 2020/1/01 |