Literaturnachweis - Detailanzeige
| Autor/inn/en | Zuniga-Kennedy, Miranda; Davoren, Micah; Shuffrey, Lauren C.; Luna, Ruth Ann; Savidge, Tor; Prasad, Vinay; Anderson, George M.; Veenstra-VanderWeele, Jeremy; Williams, Kent C. |
|---|---|
| Titel | Intestinal Predictors of Whole Blood Serotonin Levels in Children with or without Autism |
| Quelle | In: Journal of Autism and Developmental Disorders, 52 (2022) 9, S.3780-3789 (10 Seiten)
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| Zusatzinformation | ORCID (Veenstra-VanderWeele, Jeremy) |
| Sprache | englisch |
| Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
| ISSN | 0162-3257 |
| DOI | 10.1007/s10803-022-05597-w |
| Schlagwörter | Children; Autism; Pervasive Developmental Disorders; Biochemistry; Genetics; Adolescents; Males; Symptoms (Individual Disorders); Human Body; Physiology |
| Abstract | Hyperserotonemia, or elevated levels of whole blood serotonin (WB5-HT), was the first biomarker linked to autism spectrum disorder (ASD). Despite numerous studies investigating the etiology of hyperserotonemia, results have been inconsistent. Recent findings suggest a relationship between the immune system and hyperserotonemia. The current study investigated whether intestinal 5-HT levels, 5-HT gene expression, or intestinal cell types predict WB5-HT. Participants included thirty-one males aged 3-18 who were classified into one of three groups: ASD and functional GI issues, typically developing with GI issues, and typically developing without GI issues. Samples from a lower endoscopy were analyzed to examine the pathways in predicting WB-5HT. Results demonstrated an association between T-Lymphocytes and WB5-HT. (As Provided). |
| Anmerkungen | Springer. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/ |
| Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
| Update | 2024/1/01 |
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