Ageing and Cognition in Men with Fragile X Syndrome

Autor/inn/en	Sauna-aho, Oili; Bjelogrlic-Laakso, Nina; Rautava, Päivi; Arvio, Maria
Titel	Ageing and Cognition in Men with Fragile X Syndrome
Quelle	In: Journal of Applied Research in Intellectual Disabilities, 33 (2020) 5, S.1113-1118 (6 Seiten)Infoseite zur Zeitschrift PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Sauna-aho, Oili)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1360-2322
DOI	10.1111/jar.12733
Schlagwörter	Aging (Individuals); Schemata (Cognition); Males; Intellectual Disability; Longitudinal Studies; Raw Scores; Neuropsychology; Adolescents; Adults; Cognitive Ability; Leiter International Performance Scale + Suchen Sie Ihr Suchwort? Aging; Altern; Cognition; Schema; Kognition; Male; Männliches Geschlecht; Intellect; Disability; Disabilities; Verstand; Behinderung; Longitudinal study; Longitudinal method; Longitudinal methods; Längsschnittuntersuchung; Neuropsychologie; Adolescent; Adolescence; Adoleszenz; Jugend; Jugendalter; Jugendlicher; Denkfähigkeit
Abstract	Background: Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability. The aim of our longitudinal study was to describe ageing-related cognitive changes in men with FXS. Method: A neuropsychologist determined the raw scores (RSs) of 19 men with FXS twice with the Leiter International Performance Scale at an average interval of 22 years. The ages of the participants at baseline ranged from 16 to 50 (mean 27) years. Results: At follow-up, the RSs improved in two men, remained the same in two men and declined in 15 men. Overall, the RS of the study group deteriorated by an average 4 points in RSs (p < 0.001). Conclusion: Cognitive ageing in men with FXS started earlier than that in men in the general population; in many cases, cognitive ageing in men with FXS began before middle age, usually without any medical or other underlying cause. (As Provided).
Anmerkungen	Wiley. Available from: John Wiley & Sons, Inc. 111 River Street, Hoboken, NJ 07030. Tel: 800-835-6770; e-mail: cs-journals@wiley.com; Web site: https://www.wiley.com/en-us
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01