Infantile Spasms: The Role of Prenatal Stress and Altered GABA Signaling

Autor/inn/en	Schuck, Maria; Swanson, Christina I.
Titel	Infantile Spasms: The Role of Prenatal Stress and Altered GABA Signaling
Quelle	In: HAPS Educator, 23 (2019) 2, S.420-425 (7 Seiten) PDF als Volltext kostenfreie Datei Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	2473-3806
Schlagwörter	Epilepsy; Infants; Stress Variables; Prenatal Influences; Genetic Disorders; Neurological Organization; Neurological Impairments; Brain; Pregnancy; Physiology + Suchen Sie Ihr Suchwort? Epilepsie; Infant; Toddler; Toddlers; Kleinkind; Pränataler Einfluss; Neurodegenerative Erkrankung; Gehirn; Schwangerschaft; Physiologie
Abstract	Infantile spasms (IS) is a rare epileptic disorder occurring in children under the age of one that can often lead to severe developmental delays throughout life. Though over 200 etiologies have been associated with this disorder, many cases remain unexplained. Research into the etiology of IS has implicated causes such as exposure to prenatal stress or changes in GABAergic signaling. Here, we describe recent findings that draw a direct connection between prenatal stress, altered GABA signaling, and the development of IS. We also discuss how these findings can be used in the classroom to enrich discussions of nervous system physiology, development, and disease. (As Provided).
Anmerkungen	Human Anatomy and Physiology Society. PO Box 2945, LeGrange, GA 30421. e-mail: editor@hapsconnect.org; Web site: https://www.hapsweb.org/page/hapsed_home
Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01