Caudate Nucleus-Dependent Navigation Strategies Are Associated with Increased Risk-Taking and Set-Shifting Behavior

Autor/inn/en	Aumont, Étienne; Blanchette, Caroll-Ann; Bohbot, Veronique D.; West, Greg L.
Titel	Caudate Nucleus-Dependent Navigation Strategies Are Associated with Increased Risk-Taking and Set-Shifting Behavior
Quelle	In: Learning & Memory, 26 (2019) 4, S.101-108 (8 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
DOI	10.1101/lm.048306.118
Schlagwörter	Memory; Brain Hemisphere Functions; Memorization; Navigation; Decision Making; Risk; Cognitive Ability; Cognitive Tests; Abstract Reasoning; Executive Function; Spatial Ability; Responses; College Students; Foreign Countries; Canada (Montreal); Wisconsin Card Sorting Test + Suchen Sie Ihr Suchwort? Gedächtnis; Gedächtnistraining; Decision-making; Entscheidungsfindung; Risiko; Denkfähigkeit; Kognitiver Fähigkeitstest; Abstraktes Denken; Denken; Räumliches Vorstellungsvermögen; Collegestudent; Ausland
Abstract	When people navigate, they use strategies dependent on one of two memory systems. The hippocampus-based spatial strategy consists of using multiple landmarks to create a cognitive map of the environment. In contrast, the caudate nucleus-based response strategy is based on the memorization of a series of turns. Importantly, response learners display more gray matter and functional activity in the caudate nucleus and less gray matter in the hippocampus. In parallel, the caudate nucleus is involved in decision-making by mediating attention toward rewards and in set-shifting by mediating preparatory actions. The present study, therefore, examined the link between navigational strategy use, that are associated with gray matter differences in the caudate nucleus and hippocampus, and decision-making and set-shifting performance. Fifty-three participants completed the 4 on 8 virtual maze, the Iowa Gambling Task (IGT), the Wisconsin Card Sorting Test-64 (WCST-64), and a task-switching test. The results revealed that people who use response strategies displayed increased risk-taking behavior in the IGT compared to the people using hippocampus-dependent spatial strategies. Response strategy was also associated with enhanced set-shifting performance in the WCST-64 and task-switching test. These results confirm that risk-taking and set-shifting behavior, that are differentially impacted by the caudate nucleus and hippocampus memory systems, can be predicted by navigational strategy. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01