Literaturnachweis - Detailanzeige
| Autor/inn/en | Rubenstein, Eric; Young, Jessica C.; Croen, Lisa A.; DiGuiseppi, Carolyn; Dowling, Nicole F.; Lee, Li-Ching; Schieve, Laura; Wiggins, Lisa D.; Daniels, Julie |
|---|---|
| Titel | Brief Report: Maternal Opioid Prescription from Preconception through Pregnancy and the Odds of Autism Spectrum Disorder and Autism Features in Children |
| Quelle | In: Journal of Autism and Developmental Disorders, 49 (2019) 1, S.376-382 (7 Seiten)
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| Zusatzinformation | ORCID (Rubenstein, Eric) |
| Sprache | englisch |
| Dokumenttyp | gedruckt; online; Zeitschriftenaufsatz |
| ISSN | 0162-3257 |
| DOI | 10.1007/s10803-018-3721-8 |
| Schlagwörter | Mothers; Narcotics; Autism; Pervasive Developmental Disorders; Pregnancy; Brain; Risk; Correlation; Drug Therapy; Case Studies; Prenatal Influences; Child Development |
| Abstract | Opioid use during pregnancy is associated with suboptimal pregnancy outcomes. Little is known about child neurodevelopmental outcomes. We examined associations between maternal opioid prescriptions preconception to delivery (peri-pregnancy) and child's risk of ASD, developmental delay/disorder (DD) with no ASD features, or ASD/DD with autism features in the Study to Explore Early Development, a case-control study of neurodevelopment. Preconception opioid prescription was associated with 2.43 times the odds of ASD [95% confidence interval (CI) 0.99, 6.02] and 2.64 times the odds of ASD/DD with autism features (95% CI 1.10, 6.31) compared to mothers without prescriptions. Odds for ASD and ASD/DD were non-significantly elevated for first trimester prescriptions. Work exploring mechanisms and timing between peri-pregnancy opioid use and child neurodevelopment is needed. (As Provided). |
| Anmerkungen | Springer. Available from: Springer Nature. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/ |
| Erfasst von | ERIC (Education Resources Information Center), Washington, DC |
| Update | 2020/1/01 |
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