Symptoms of Autism in Males with Fragile X Syndrome: A Comparison to Nonsyndromic ASD Using Current ADI-R Scores

Autor/inn/en	McDuffie, Andrea; Thurman, Angela John; Hagerman, Randi J.; Abbeduto, Leonard
Titel	Symptoms of Autism in Males with Fragile X Syndrome: A Comparison to Nonsyndromic ASD Using Current ADI-R Scores
Quelle	In: Journal of Autism and Developmental Disorders, 45 (2015) 7, S.1925-1937 (13 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-013-2013-6
Schlagwörter	Autism; Pervasive Developmental Disorders; Genetic Disorders; Symptoms (Individual Disorders); Males; Mental Retardation; Diagnostic Tests; Severity (of Disability); Children; Comparative Analysis; Child Behavior + Suchen Sie Ihr Suchwort? Autismus; Psychiatrische Symptomatik; Male; Männliches Geschlecht; Geistige Behinderung; Diagnostic test; Diagnostischer Test; Schweregrad; Child; Kind; Kinder
Abstract	Symptoms of autism are frequent in males with fragile X syndrome (FXS), but it is not clear whether symptom profiles differ from those of nonsyndromic ASD. Using individual item scores from the Autism Diagnostic Inventory-Revised, we examined which current symptoms of autism differed in boys with FXS relative to same-aged boys diagnosed with nonsyndromic ASD. In addition, different subsamples of participants were matched on autism diagnostic status and severity of autism symptoms. Between-group comparisons revealed that boys with FXS showed significantly less impairment in Social Smiling than did age-, diagnostic-, and severity-matched boys with nonsyndromic ASD. Severity-matched boys with FXS showed more impairment in complex mannerisms than did boys with nonsyndromic ASD. Behavioral differences between FXS and nonsyndromic ASD may be of theoretical importance in understanding the causes and correlates of ASD in FXS and in developing and implementing appropriate treatments. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01