Effects of Sleep Deprivation and Aging on Long-Term and Remote Memory in Mice

Autor/inn/en	Vecsey, Christopher G.; Park, Alan J.; Khatib, Nora; Abel, Ted
Titel	Effects of Sleep Deprivation and Aging on Long-Term and Remote Memory in Mice
Quelle	In: Learning & Memory, 22 (2015) 4, S.197-202 (6 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1072-0502
DOI	10.1101/lm.036590.114
Schlagwörter	Sleep; Memory; Neurological Impairments; Animals; Age Differences; Genetics; Brain Hemisphere Functions; Training; Experiments; Control Groups + Suchen Sie Ihr Suchwort? Schlaf; Gedächtnis; Neurodegenerative Erkrankung; Animal; Tier; Tiere; Age; Difference; Age difference; Altersunterschied; Humangenetik; Ausbildung; Erprobung
Abstract	Sleep deprivation (SD) following hippocampus-dependent learning in young mice impairs memory when tested the following day. Here, we examined the effects of SD on remote memory in both young and aged mice. In young mice, we found that memory is still impaired 1 mo after training. SD also impaired memory in aged mice 1 d after training, but, by a month after training, sleep-deprived and control aged animals performed similarly, primarily due to remote memory decay in the control aged animals. Gene expression analysis supported the finding that SD has similar effects on the hippocampus in young and aged mice. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2020/1/01