Dietary Status and Impact of Risperidone on Nutritional Balance in Children with Autism: A Pilot Study

Autor/inn/en	Lindsay, Ronald L.; Arnold, L. Eugene; Aman, Michael G.; Vitiello, Benedetto; Posey, David J.; McDougle, Christopher J.; Scahill, Lawrence; Pachler, Maryellen; McCracken, James T.; Tierney, Elaine; Bozzolo, Dawn
Titel	Dietary Status and Impact of Risperidone on Nutritional Balance in Children with Autism: A Pilot Study
Quelle	In: Journal of Intellectual and Developmental Disability, 31 (2006) 4, S.204-209 (6 Seiten) PDF als Volltext Verfügbarkeit
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	1366-8250
Schlagwörter	Autism; Nutrition; Behavior Disorders; Children; Adolescents; Outcomes of Treatment; Body Weight; Eating Habits; Drug Therapy + Suchen Sie Ihr Suchwort? Autismus; Ernährung; Child; Kind; Kinder; Adolescent; Adolescence; Adoleszenz; Jugend; Jugendalter; Jugendlicher; Körpergewicht; Ernährungsgewohnheit; Essgewohnheit
Abstract	Background: Risperidone may be effective in improving tantrums, aggression, or self-injurious behaviour in children with autism, but often leads to weight gain. Method: Using a quantitative Food Frequency Questionnaire (FFQ), we prospectively examined the nutritional intake of 20 children with autism participating in a randomised placebo-controlled trial of risperidone for disruptive behaviours. Results: At baseline, the mean intakes for macronutrients, vitamins and minerals exceeded Dietary Reference Intakes (DRIs). However there was substantial inter-participant variability, with individual deficiencies ([less than]80% of DRI) in the intake of calcium (9 of 20 participants), pantothenic acid (6 of 20), vitamin D (5 of 20) and vitamin K (8 of 20). For the participants for whom FFQs were available, there was an increase in weight and an increase in vitamin K intake after 2 months of risperidone treatment (n=9) compared to placebo (n=8). An additional 4 months of risperidone treatment (n=8) did not result in significant changes in reported nutritional balance. Conclusion: These pilot data suggest that treatment with risperidone did not significantly affect the nutritional balance of this small group of children. (Contains 2 tables and 1 figure.) (Author).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2017/4/10